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THE TUMOR MICROENVIRONMENT OF HIGH GRADE SEROUS OVARIAN CANCER

septiembre 29, 2020

THE TUMOR MICROENVIRONMENT OF HIGH GRADE SEROUS OVARIAN CANCER descargar PDF gratis

Datos del ebook

Encuadernación:
Sin formato definido
ISBN:
9783038975540

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Sinopsis de THE TUMOR MICROENVIRONMENT OF HIGH GRADE SEROUS OVARIAN CANCER

The Special Issue on high grade serous ovarian cancer HGSOC and the contribution of the tumor microenviroment TME consists of reviews contributed by leaders in the OC field As HGSOC metastases have a highly complex TME there is an urgent need to better understand the TME in normal its distinct components in particular and the role of the TME in the context of disease recurrence and development of chemoresistance The Special Issue incorporates the current understanding of the different parts of thd TME components including the cancer cells themselves the cells surrounding the cancer cells or stromal cells and the cells of the immune system which are attracted to the site of metastases  In addition to these cells of the TME the role of various cellular factors  made by the cells of the TME are also  the subject of the reviews In addition reviews in this Special Issue cover the complex relationships between the molecular mechanisms of HGSOC progression including genomic epigenomic and transcriptomic changes and changes in the immune cell landscape as these may provide attractive new molecular targets for HGSOC therapy
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